Immunohistochemical identification of lysozyme in intestinal lesions in ulcerative colitis and Crohn's disease.

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Immunohistochemical identification of lysozyme in intestinal lesions in ulcerative colitis and Crohn's disease.

Lysozyme (LZM) was identified in ulcerative colitis in granulocytes, monocytes, and macrophages of the intestinal lamina propria. In contrast with findings in normal colon or rectum, in ulcerative colitis LZM was also detected in some mucosal crypt cells and metaplastic Paneth cells. In both ulcerative colitis and Crohn's disease LZM was present in inflammatory cells of crypt abscesses. In Croh...

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Ulcerative colitis and Crohns disease: molecular genetics and clinical implications.

Derek Jewell Professor of Gastroenterology, Gastroenterology Unit, Radcliffe Infirmary, Oxford, OX2 6HE, UK. Tel: +44 (0) 1865 224829; Fax: +44 (0) 1865 790792; E-mail: [email protected] The genetics of inflammatory bowel disease (IBD) is an area of enormous topical interest. Crohn’s disease is one of the first polygenic diseases in which a susceptibility gene (NOD2 ) ...

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Skin lesions in ulcerative colitis.

This paper is a study of the skin complications of ulcerative colitis. Between theyearsl949and 1965,415 patients, 230 women and 185 men, were admitted to the Central Middlesex Hospital suffering from this disease. Our object has been to determine the incidence and pattern of the skin disorders in this group and to try to discover if there is any relationship between the skin disease and the sev...

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Pulmonary function in ulcerative colitis

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ژورنال

عنوان ژورنال: Gut

سال: 1977

ISSN: 0017-5749

DOI: 10.1136/gut.18.5.377